cocaine dependence การใช้

• It has been promoted as an adjuvant for the treatment of cocaine dependence.
• Cocaine dependence is associated with depleted dopamine levels in the central nervous system.
• Measures of Attentional Bias and Relational Responding Are Associated with Behavioral Treatment Outcome for Cocaine Dependence.
• Despite years of research, there is no drug approved in the United States for treating cocaine dependence.
• It has also been tried, albeit with little evidence of efficacy, in the treatment of cocaine dependence.
• The pilot 8-week double-blind study of modafinil for cocaine dependence ( 2004 ) produced inconclusive results.
• Vanoxerine has been researched for use in treating cocaine dependence both as a substitute for cocaine and to block the rewarding effects.
• The antidepressants Prozac and Effexor, which boost levels of yet another brain chemical called serotonin, are also under study in cocaine dependence.
• Bupropion has shown no effectiveness in the treatment of cocaine dependence, but there is weak evidence that it may be useful in treating methamphetamine dependence.
• As of 2012, clinical trials to assess nepicastat as a treatment for post-traumatic stress disorder ( PTSD ) and cocaine dependence have been completed.
• Cocaine dependence is a form of psychological dependence that develops from regular cocaine use and produces a withdrawal state with emotional-motivational deficits upon cessation of cocaine use.
• It is thought these effects are mediated via a partial agonist action at Alpha-2 adrenergic receptors, and TDIQ has been suggested as a possible drug for the treatment of cocaine dependence.
• "It's also worth noting that for some time now the international classification of diseases published by WHO has identified tobacco dependence as a disease in the same class as heroin dependence and cocaine dependence,"
• PARIS ( Dow Jones / AP ) _ Several prominent scientists from pharmaceutical giants GlaxoSmithKline and Roche Holding are breaking away from their parent companies to form a Swiss firm focusing on compounds for nicotine, alcohol and cocaine dependence.
• Researchers there have shown that the heroin substitute methadone can bring the brain of heroin users back into equilibrium; they have traced the way marijuana can actually rewire users'brains; and they are searching for therapies for cocaine dependence.
• Fran鏾is Truffaut, one of French cinema's most iconic directors and a star of " Close Encounters ", blamed her for that film's budget difficulties, and she was eventually fired during post-production because of her cocaine dependence.
• Those animals who are allowed to self-administer for 6 hours a day show behavior that is thought to resemble cocaine dependence, such as an escalation of the total dose taken during each session and an increase in the dose taken when cocaine is first made available.
• To elaborate, if a person is addicted to three separate substance such as cocaine, methamphetamines and alcohol and is dependent on all three then they would be diagnosed with three separate dependence disorders existing together ( cocaine dependence, methamphetamine dependence and alcohol dependence, ) not polysubstance dependence.
• However, SDRAs like PAL-542 would, in theory, be expected to produce fewer side effects ( including sympathomimetic / cardiovascular effects, insomnia, hyperthermia, and anxiety ) relative to SNDRAs, and thus would likely be comparatively more favorable in the treatment of cocaine dependence and other conditions.
• A later double-blind study of modafinil in people seeking treatment for cocaine dependence found no statistically significant effect on the rate of change in percentage of cocaine non-use days, but noted a significant improvement in some secondary outcomes such as the maximum number of consecutive non-use days for cocaine.